Table 1. Composition of different self nanoemulsifying systems with different oils:surfactant:co-surfactant ratios and their measured dependent responses .
| System |
Labrafil
®
M
Oily phase (%; w/w) |
Capryol ™ 90
Oily phase (%; w/w) |
Tween
®
80
Surfactant (%; w/w) |
Transcutol
®
HP
Co-surfactant (%; w/w) |
Terconazole solubilty
(mg/mL) |
Globule size
(nm) |
PDI | Self-emulsification time (s) |
| SNES L1 | 10 | 80 | 10 | 26.00 | - | - | - | |
| SNES L2 | 10 | 70 | 20 | 42.60 | - | - | - | |
| SNES L3 | 10 | 60 | 30 | 50.25 | - | - | - | |
| SNES L4 | 10 | 50 | 40 | 57.00 | - | - | - | |
| SNES L5 | 20 | 70 | 10 | - | - | - | - | |
| SNES L6 | 20 | 60 | 20 | 42.40 | - | - | - | |
| SNES L7 | 20 | 50 | 30 | 72.70 | 15.13 ± 0.34 | 0.07 ± 0.01 | 12.80 | |
| SNES L8 | 20 | 40 | 40 | 71.00 | 20.26 ± 0.08 | 0.10 ± 0.01 | 14.34 | |
| SNES C1 | 10 | 80 | 10 | 36.00 | - | - | - | |
| SNES C2 | 10 | 70 | 20 | 39.93 | - | - | - | |
| SNES C3 | 10 | 60 | 30 | 54.25 | - | - | - | |
| SNES C4 | 10 | 50 | 40 | 58.50 | - | - | - | |
| SNES C5 | 20 | 70 | 10 | 47.80 | - | - | - | |
| SNES C6 | 20 | 60 | 20 | 61.90 | 59.87 ± 0.16 | 0.12 ± 0.02 | 29.82 | |
| SNES C7 | 20 | 50 | 30 | 72.50 | 59.00 ± 1.36 | 0.09 ± 0.01 | 31.13 | |
| SNES C8 | 20 | 40 | 40 | - | - | - | - | |
| SNES C9 | 20 | 30 | 50 | - | - | - | - | |
| SNES C10 | 20 | 20 | 60 | - | - | - | - |
PDI, poly dispersity index