Table 2.
Most similar Drosophila melanogaster protein to each predicted Homarus americanus neuromodulator biosynthetic enzyme sequence
| Homarus americanus protein | Top FlyBase D. melanogaster annotated protein hit | ||||
|---|---|---|---|---|---|
| Modulator class | Query protein | Accession No. | Name | BLAST statistics | |
| Score | E-value | ||||
| Peptide | Homam-SPP | AAF51486 | Signal peptide peptidase | 463 | 2e-130 |
| Homam-PPP | AAF56615 | Amontillado | 966 | 0.0 | |
| Homam-CP* | AAF45514 | Silver, isoform B | 832 | 0.0 | |
| Homam-QC | AAO41279 | Iso glutaminyl cyclase, isoform A | 287 | 2e-77 | |
| Homam-TPST | AAF48286 | Transport and golgi organization 13, isoform B | 473 | 2e-133 | |
| Homam-PDI-v1 | AAF49659 | Protein disulfide isomerase, isoform A | 616 | 2e-176 | |
| Homam-PDI-v2 | AAF49659 | Protein disulfide isomerase, isoform A | 614 | 1e-175 | |
| Homam-PHM | AAF47127 | Peptidylglycine-α-hydroxylating monooxygenase, isoform A | 371 | 1e-102 | |
| Homam-PAL-I-v1 | AAF58870 | Peptidyl-α-hydroxyglycine-α-amidating lyase 1, isoform A | 297 | 4e-80 | |
| Homam-PAL-I-v2 | AAF58870 | Peptidyl-α-hydroxyglycine-α-amidating lyase 1, isoform A | 298 | 3e-80 | |
| Homam-PAL-II | AAF47043 | Peptidyl-α-hydroxyglycine-α-amidating lyase 2, isoform A | 270 | 2e-72 | |
| Amine | Homam-TPH-v1 | AAF50517 | Henna, isoform A | 669 | 0.0 |
| Homam-TPH-v2 | AAF50517 | Henna, isoform A | 657 | 0.0 | |
| Homam-TPH-v3 | AAF50517 | Henna, isoform A | 666 | 0.0 | |
| Homam-TPH-v4 | AAF50517 | Henna, isoform A | 665 | 0.0 | |
| Homam-TH | AAN12080 | Pale, isoform A | 641 | 0.0 | |
| Homam-DDC | AAF53762 | DOPA decarboxylase, isoform C | 640 | 0.0 | |
| Homam-TDC | AAM70812 | Tyrosine decarboxylase 2 | 779 | 0.0 | |
| Homam-TBH | AAO41640 | Tyramine β-hydroxylase, isoform B | 471 | 1e-132 | |
| Homam-TRH | AAF47444 | Tryptophan hydroxylase | 639 | 0.0 | |
| Homam-HDC* | AAF58823 | Histidine decarboxylase, isoform A | 854 | 0.0 | |
| Gas | Homam-NOS-v1 | AAF53014 | Nitric oxide synthase, isoform A | 1361 | 0.0 |
| Homam-NOS-v2 | AAF53014 | Nitric oxide synthase, isoform A | 1364 | 0.0 | |
| Homam-NOS-v3 | AAF53014 | Nitric oxide synthase, isoform A | 1368 | 0.0 | |
| Homam-NOS-v4 | AAZ66454 | Nitric oxide synthase, isoform F | 806 | 0.0 | |
| Homam-NOS-v5 | AAF53014 | Nitric oxide synthase, isoform A | 560 | 3e-159 | |
| Homam-HO-v1 | AAF54680 | Heme oxygenase | 163 | 3e-40 | |
| Homam-HO-v2 | AAF54680 | Heme oxygenase | 162 | 5e-40 | |
| Small molecule transmitter | Homam-CHAT | AAS65177 | Choline acetyltransferase, isoform B | 522 | 7e-148 |
| Homam-GLS-I-v1 | ACZ94404 | Glutaminase, isoform H | 698 | 0.0 | |
| Homam-GLS-I-v2 | AAM68643 | Glutaminase, isoform A | 708 | 0.0 | |
| Homam-GLS-I-v3 | AAM68647 | Glutaminase, isoform B | 663 | 0.0 | |
| Homam-GLS-I-v4 | ACZ94404 | Glutaminase, isoform H | 705 | 0.0 | |
| Homam-GLS-II-v1 | AHN56158 | Glutaminase, isoform K | 617 | 2e-176 | |
| Homam-GLS-II-v2 | AHN56158 | Glutaminase, isoform K | 617 | 2e-176 | |
| Homam-GAD-I | AAF47834 | Glutamic acid decarboxylase 1, isoform A | 680 | 0.0 | |
| Homam-GAD-II | AAF53337 | Black, isoform A | 570 | 1e-162 | |
Enzyme family abbreviations: SPP, signal peptide peptidase; PPP, prohormone processing protease; CP, carboxypeptidase; QC, glutaminyl cyclase; TPST, tyrosylprotein sulfotransferase; PDI, protein disulfide isomerase; PHM, peptidylglycine α-hydroxylating monooxygenase; PAL, peptidyl-α-hydroxyglycine-α-amidating lyase; TPH, tryptophan-phenylalanine hydroxylase; TH, tyrosine hydroxylase; DDC, DOPA decarboxylase; TDC, tyrosine decarboxylase; TBH, tyramine β-hydroxylase; TRH, tryptophan hydroxylase; HDC, histidine decarboxylase; NOS, nitric oxide synthase; HO, heme oxygenase; CHAT, choline acetyltransferase; GLS, glutaminase; GAD, glutamic acid decarboxylase.
Full-length rather than the partial proteins predicted from the transcriptome used as the query sequence (see text)