Table 4.
The number of significant nodes (p < .05, false discovery rate [FDR]‐adjusted) in each brain area identified via comparison of the betweenness centrality (BC), eigenvector centrality (EVC), clustering coefficient (CC), and nodal efficiency (NE) of the complete adjacency matrices in the theta band of patients with right‐hemispheric focal epilepsy (RPs) and patients with left‐hemispheric focal epilepsy (LPs) along with the number of nodes in each brain area of the subnetwork identified using network‐based statistics (NBS) with a 3.45 primary threshold, 5,000 random permutations, and a p < .05 significance level (family‐wise error rate [FWER]‐corrected) on the connection strengths of the complete, un‐thresholded adjacency matrices of RPs and LPs in the theta band
| Brain area (right) | NBS | Local graph measures | |||
|---|---|---|---|---|---|
| CC | NE | BC | EVC | ||
| Right middle frontal gyrus | 1 | 1 | 1 | 0 | 0 |
| Right orbital gyrus | 1 | 1 | 3 | 0 | 0 |
| Right precentral gyrus | 1 | 0 | 0 | 0 | 0 |
| Right inferior frontal gyrus | 0 | 2 | 3 | 0 | 0 |
| Right superior temporal gyrus | 1 | 1 | 3 | 0 | 0 |
| Right middle temporal gyrus | 2 | 1 | 3 | 0 | 0 |
| Right inferior temporal gyrus | 6 | 1 | 3 | 0 | 0 |
| Right fusiform gyrus | 2 | 0 | 1 | 0 | 0 |
| Right parahippocampal gyrus | 0 | 1 | 4 | 0 | 1 |
| Right superior parietal lobe | 1 | 0 | 1 | 0 | 0 |
| Right inferior parietal lobe | 2 | 1 | 0 | 0 | 0 |
| Right precuneus | 1 | 1 | 3 | 0 | 0 |
| Right insular gyrus | 3 | 2 | 2 | 0 | 0 |
| Right cingulate gyrus | 1 | 2 | 2 | 0 | 0 |
| Right medioventral occipital cortex | 2 | 1 | 1 | 0 | 0 |
| Right lateral occipital cortex | 1 | 0 | 0 | 0 | 0 |
| Right amygdala | 0 | 0 | 2 | 0 | 0 |
| Right hippocampus | 0 | 1 | 2 | 0 | 0 |
| Right basal ganglia | 1 | 4 | 5 | 0 | 0 |
| Right thalamus | 2 | 1 | 5 | 0 | 0 |
| Brain area (left) | NBS | Local graph measures | |||
|---|---|---|---|---|---|
| CC | NE | BC | EVC | ||
| Left superior frontal gyrus | 1 | 0 | 0 | 0 | 0 |
| Left orbital gyrus | 1 | 1 | 0 | 0 | 0 |
| Left inferior frontal gyrus | 0 | 0 | 0 | 1 | 1 |
| Left middle frontal gyrus | 0 | 0 | 0 | 0 | 1 |
| Left superior temporal gyrus | 0 | 0 | 0 | 3 | 4 |
| Left middle temporal gyrus | 0 | 0 | 0 | 1 | 1 |
| Left inferior temporal gyrus | 0 | 0 | 0 | 1 | 0 |
| Left fusiform gyrus | 0 | 0 | 0 | 1 | 0 |
| Left postcentral gyrus | 0 | 0 | 0 | 1 | 2 |
| Left inferior parietal lobe | 0 | 0 | 0 | 0 | 1 |
| Left precuneus | 0 | 0 | 1 | 0 | 0 |
| Left insular gyrus | 0 | 0 | 0 | 0 | 2 |
| Left medioventral occipital cortex | 1 | 0 | 0 | 0 | 0 |
| Left lateral occipital cortex | 2 | 0 | 0 | 0 | 0 |
| Left hippocampus | 0 | 0 | 0 | 0 | 1 |
| Left thalamus | 0 | 1 | 0 | 0 | 0 |
Note: The NBS network had nodes in 20 brain areas (16 in the right hemisphere and 4 in the left hemisphere) while BC identified significant nodes in 6 brain areas (all left), EVC in 9 brain areas (1 right and 8 left), CC in 17 brain areas (15 right and 2 left), and NE in 18 brain areas (17 right and 1 left). The number of brain areas that matched was 13 between the NBS network and the CC (12 right and 1 left), 13 between the NBS network and the NE (all right), 14 between the CC and NE (all right), 1 between the CC and EVC (all right), 1 between the NE and EVC (all right), and 4 between the BC and EVC (all left). Brain areas that matched between any of the NBS network, CC, NE, and EVC are in italics while brain areas that matched between the BC and EVC are in boldface.
Abbreviations: CC, clustering coefficient; BC, betweenness centrality; EVC, eigenvector centrality; NBS, network‐based statistics; NE, nodal efficiency.