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Boxplots showing the differences in global network measures between HCs (white) and PMS patients (grey) for both raw and COMMIT tractograms. We observe that after the application of COMMIT the differences between HC and PMS patients are more pronounced. Also, the presence of outliers is often mitigated when COMMIT is applied. COMMIT, convex optimization modelling for microstructure informed tractography; HCs, healthy controls; PMS, progressive multiple sclerosis
