Table 1.
Global graph metrics of HCs and PMS patients computed on the raw connectomes
| HC (n = 24) | PMS (n = 42) | p a | p b | |
|---|---|---|---|---|
| Modularity | 0.39 ± 0.03 | 0.46 ± 0.06 | <.001 | <.001 |
| Global efficiency | 1997.23 ± 242.51 | 1,716.31 ± 379.93 | .003 | .024 |
| Clustering coefficient | 2,376.28 ± 281.07 | 2,340.14 ± 385.03 | .958 | .327 |
| Mean strength | 14,726.32 ± 1,742.35 | 12,701.39 ± 2,682.28 | .002 | .017 |
| Assortativity | −0.13 ± 0.02 | −0.12 ± 0.03 | .113 | .208 |
| Density | 0.94 ± 0.02 | 0.91 ± 0.08 | .055 | – |
Abbreviations: HCs, healthy controls; PMS, progressive multiple sclerosis.
Note: All values are expressed as mean ± SD; ANCOVA age and gender corrected (p a), ANCOVA age, gender and density corrected (p b). Statistically significant p values after Bonferroni correction are highlighted in bold.