Figure 7.

Illustrative patient with focal seizures originating from the right frontal parasagittal cortex (Patient 18). The first row corresponds to Study 1, the second row corresponds to Study 3 (see supplementary material for further details). From left to right, interictal epileptiform discharges (IEDs) average, topography at the peak, unthresholded source localization results obtained with Ave, coherent maximum entropy on the mean (cMEM), minimum norm estimate (MNE), dynamic statistical parametric mapping (dSPM), and standardized low‐resolution electromagnetic tomography (sLORETA). Source localization was performed at the peak. The example shows that distributed magnetic source imaging (dMSI) is sometimes able to reconstruct recover an accurate source also when the signal to noise ratio is not ideal and the topographical distribution is complex (first raw). Conversely, source localization might be inaccurate, at times with the maximum localized in the opposite hemisphere even when the signal to noise ratio is high and the topographical distribution is dipolar (lower row). This often occurs when the source is close to the midline