Table 2.
Frequencies and absolute count of B cells subsets and significance levels in patients grouped by post vaccination serum levels of Anti-PnPs IgA as IgA non-responders (NR) and IgA responders (R).
| IgA-NR | IgA-R | P-value | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
|
B cells CD19+ | |||||
| % Lymphocytes | 9.9 | 6.7 | 13.5 | 7.0 | 0.063 |
| B cell/mm3 | 191.7 | 181.8 | 239.4 | 218.2 | 0.336 |
|
Naive B cells CD27-IgM+IgD+ | |||||
| % B cells | 73.4 | 22.9 | 57.5 | 20.2 | 0.010 |
| B cell/mm3 | 140.7 | 145.2 | 123.4 | 92.6 | 0.489 |
|
MZ B cells CD27+IgM+IgD+ | |||||
| % B cells | 15.3 | 16.1 | 27.5 | 16.2 | 0.066 |
| B cell/mm3 | 34.5 | 63.6 | 82.9 | 102.9 | 0.109 |
|
Switched memory CD27+IgM-IgD- | |||||
| % B cells | 2.7 | 3.5 | 12.5 | 5.9 | <0.0001 |
| B cell/mm3 | 4.2 | 6.2 | 24.9 | 25.4 | 0.001 |
| K/L ratio | 1.5 | 0.6 | 1.3 | 0.1 | 0.051 |
|
Transitional B CD38++IgM++ | |||||
| % B cells | 7.2 | 10.4 | 3.2 | 3.9 | 0.165 |
| B cell/mm3 | 12.0 | 25.5 | 5.1 | 3.8 | 0.386 |
|
Plasmablasts CD38+++IgM± | |||||
| % B cells | 1.7 | 2.0 | 4.1 | 10.0 | 0.117 |
| B cell/mm3 | 2.9 | 3.9 | 2.5 | 2.6 | 0.639 |
|
CD21 low B cells CD21 low CD38 low | |||||
| % B cells | 21.6 | 19.0 | 10.3 | 12.3 | 0.368 |
| B cell/mm3 | 37.5 | 50.4 | 50.5 | 108.5 | 0.057 |