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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Exp Neurol. 2019 Oct 17;323:113067. doi: 10.1016/j.expneurol.2019.113067

Figure 3:

Figure 3:

Phrenic motor neuron counts at Day 8 post-intrapleural cholera toxin (CtB-Saporin) injections (50 μg/rat total). A-C: Representative images (20x) for CtB-labelled phrenic motor neurons. D: CtB-Saporin causes almost complete loss of phrenic motor neurons (p<0.01 vs control; asterisk). Adenosine 2A (A2a) receptor antagonist (Istradefylline; KW6002) administration following intrapleural CtB-Saporin injections improves phrenic motor neuron survival versus CtB-Saporin injected + vehicle treated rats (p<0.05; #). Mean ± 1 SEM. Scale bar = 40 μm.