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. 2020 Jun 27;2020:3985315. doi: 10.1155/2020/3985315

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Copyright © 2020 Fani Ziouti et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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PCE-CT for bone ultrastructural characterization of femora injected with PBS (a, b) versus MOPC315.BM.Luc cells (c, d) at day 21. (a, c) PCE-CT images of cross sections of femur metaphysis. (c) Numerous sites of erosion (black arrows) and bone loss are indicated in the femur of the MM-injected bone. (b, d) High-magnification view of the rectangular area in (a) and (c). (d) Rectangular area of a local region in the cortex reveals multiple zones of intensive bone remodeling activity, with low-density new bone (darker grey, indicated with #) intermixed with mature bone sites (brighter grey), pocked with irregular-shaped “punched-out” lesions (black arrows).