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. 2020 May 5;217(7):e20191369. doi: 10.1084/jem.20191369

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© 2020 Santos et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

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Figure S1. — Associations of MA expression levels in the DC vaccines with survival time and clinical responses. (A) Scatter plots showing correlations between TYR (Tyrosinase) and MLANA (MART-1; in the same expression cassette), TYR and MAGEA6 (MAGE-A6; separate cassettes; equivalence test for R > −0.3 and R < 0.3; P = 0.258) and MLANA and MAGEA6 (separate cassettes; equivalence test for R > −0.3 and R < 0.3; P = 0.215) based on mRNA expression measured in the DC vaccines. Pearson correlation coefficient (R), with P values and 95% confidence intervals indicated. (B) Univariate Cox regression analyses for DC vaccine–MA antigen expression levels and OS and PFS. (C) Univariate Cox regression analysis for associations between MA-specific IFN-γ release (ELISPOT counts) from total PBMCs isolated at baseline (d0) or after vaccine (d43) and OS and PFS.