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. 2020 Jun 21;26(23):3182–3200. doi: 10.3748/wjg.v26.i23.3182

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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The enteric nervous system mechanism of acupuncture. Stimulation at ST37 and ST25 had different effects on colonic motility in terms of the effects on excitatory and inhibitory neurons in the enteric nervous system. A: Sympathetic pathway; B: Parasympathetic pathway; 1: Inhibitory neurons; 2: Excitatory neurons; 3: Myenteric intrinsic primary afferent neurons; 4: Submucosal intrinsic primary afferent neurons; 5: Secretomotor/vasodilator neurons; LM: Longitudinal muscle; MP: Myenteric plexus; CM: Circular muscle; (+): Effective, (−): Ineffective[72]; ENS: Enteric nervous system.