Table 1:

Patient sample demographic characteristics. Presented in mean ± SEM.

	Age	%Female	BMI	Eroded cartilage OARSI score	Intact cartilage OARSI score
16s Deep-sequencing cohort
Hip
OA (n=34)	65 ± 2	58%	29 ± 1*	13 ± 1	3.3 ± 0.6
Control (n=10)	66 ± 3	40%	27 ± 2	n/a	1.5 ± 0.5
Knee
OA (n=21)	59 ± 2*	57%	34 ± 1*	15 ± 1*	2.9 ± 0.6
Control (n=10)	68 ± 4*	40%	30 ± 3	n/a	0.0 ± 0.0
qPCR confirmation cohort
Hip
OA (n=5)	67 ± 5	60%	25 ± 1	9 ± 1	1.0 ± 0.3
Control (n=5)	54 ± 4	20%	33±3	n/a	0.0 ± 0.0
Knee
OA (n=5)	60 ± 4	20%	35 ± 1	10 ± 2*	2.0 ± 1.7
Control (n=5)	59 ± 4	20%	32 ± 1	n/a	0.0 ± 0.0

^*Statistically significant differences:

Knee OA vs. knee control age: p=0.03

Hip OA vs. knee OA BMI: p=0.01

Knee 16s cohort eroded vs. knee qPCR confirmation cohort eroded OARSI score: p=0.05