Table 1.

Median IQR and P-Value of features corrected for all acquisition parameters, age and gender P -values of the Mann Whitney 2 samples test across IDH status and Grade are reported

	WT		IDH		P WT vs IDH	Grade II		Grade III		Grade IV		Comparisons
	Median	IQR	Median	IQR		Median	IQR	Median	IQR	Median	IQR	II vs III	II vs IV	III vs IV
Volume	48,462.5	48,106	46,925	65,232.5	0.091	45,811	65,213	39,962.5	51,400.5	52,035.5	51,967.5	0.311	0.468	0.238
Surface	10,246	9723.750	9402	9677	0.445	8756	9352	8047.5	9546.25	10,631.5	9711.75	0.367	0.053	0.143
SAV	0.225	0.080	0.200	0.08	< 0.0005	0.198	0.083	0.218	0.093	0.224	0.084	0.010	< 0.0005	0.252
NonCompactness	21.008	10.766	18.942	9.433	0.002	17.992	7.745	19.651	10.69	21.884	11.397	0.021	< 0.0005	0.063
Mean	0.014	0.550	−0.199	0.592	< 0.0005	−0.185	0.517	−0.158	0.568	0.029	0.582	0.338	< 0.0005	0.001
Skewness	−0.183	0.802	0.198	0.792	< 0.0005	0.209	0.79	0.165	0.781	−0.232	0.756	0.157	< 0.0005	< 0.0005
TabKurtosis	−1.348	3.540	0.344	3.853	< 0.0005	0.11	3.737	0.471	4.501	−1.527	3.468	0.433	< 0.0005	< 0.0005
Min	0.008	0.355	−0.026	0.37	0.030	−0.001	0.425	−0.021	0.33	−0.006	0.385	0.342	0.341	0.198
Max	−0.089	1.175	−0.053	1.316	0.470	−0.075	1.248	−0.013	1.296	−0.096	1.195	0.314	0.481	0.334
STD	0.008	0.418	−0.055	0.345	0.002	−0.04	0.347	−0.086	0.356	0.006	0.417	0.167	0.025	0.002
P1	0.031	0.389	−0.046	0.416	0.035	−0.01	0.405	−0.021	0.409	0.021	0.401	0.335	0.264	0.168
P5	0.033	0.377	−0.049	0.426	0.025	−0.036	0.409	0.016	0.423	0.027	0.391	0.461	0.095	0.161
P25	0.061	0.431	−0.093	0.45	< 0.0005	− 0.049	0.458	− 0.045	0.421	0.039	0.463	0.184	0.001	0.030
TaP50	0.044	0.499	−0.194	0.555	< 0.0005	−0.158	0.516	−0.152	0.566	0.052	0.561	0.146	< 0.0005	0.003
P75	0.018	0.798	−0.295	0.737	< 0.0005	−0.278	0.689	−0.247	0.755	0.028	0.842	0.266	< 0.0005	< 0.0005
P95	0.084	1.312	−0.376	1.350	< 0.0005	−0.216	1.403	−0.405	1.278	0.093	1.351	0.207	0.003	0.001
P99	0.186	1.405	−0.211	1.529	0.001	−0.068	1.568	−0.31	1.451	0.186	1.37	0.116	0.083	0.002
ASM	−0.004	0.008	−0.002	0.0100	0.001	−0.002	0.01	−0.003	0.006	−0.004	0.009	0.281	0.001	0.007
Contrast	−4.890	18.634	−4.279	15.036	0.062	−3.672	17.134	−5.711	13.839	−4.179	18.677	0.123	0.263	0.045
Correlation	−1.113	8.802	1.907	8.196	< 0.0005	0.828	8.248	2.729	7.336	−1.113	9.016	0.107	0.001	< 0.0005
SumSquare	−19.125	597.816	−225.235	594.281	< 0.0005	−209.191	525.299	− 177.068	606.613	18.931	630.678	0.393	< 0.0005	0.001
SumAverage	0.444	10.685	−3.779	11.507	< 0.0005	−3.615	10.26	−2.983	10.843	0.505	11.502	0.338	< 0.0005	0.001
IDifferenceMoment	−0.023	0.118	0.016	0.112	< 0.0005	0.02	0.125	0.012	0.118	− 0.019	0.112	0.112	< 0.0005	0.002
Sum Entropy	−0.086	0.406	0.039	0.412	< 0.0005	0.039	0.409	0.07	0.424	−0.082	0.397	0.412	< 0.0005	0.001
Entropy	0.156	0.747	−0.09	0.717	< 0.0005	−0.09	0.663	−0.119	0.805	0.176	0.688	0.277	< 0.0005	0.001
Difference Variance	−0.049	0.186	−0.043	0.150	0.062	−0.037	0.171	−0.057	0.138	−0.042	0.187	0.123	0.263	0.045
Sum Variance	9.638	2522.443	− 905.249	2537.186	< 0.0005	− 804.524	2172.045	−735.281	2522.304	71.102	2654.762	0.366	< 0.0005	0.001
difference Entropy	0.043	0.376	−0.044	0.336	< 0.0005	− 0.038	0.353	− 0.031	0.346	0.062	0.347	0.389	0.001	0.005
IMC1	−0.012	0.073	−0.001	0.062	0.053	0.005	0.053	−0.008	0.061	−0.011	0.068	0.020	0.012	0.429