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. 2020 Jun 12;44(2):599–610. doi: 10.3892/or.2020.7645

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Inhibition of the long noncoding RNA OSER1-AS1 suppresses the malignant biological phenotypes of NSCLC. (A) Determination of OSER1-AS1 expression in H522 and A549 cell lines after si-NC or si-OSER1-AS1 transfection using RT-qPCR. (B and C) Cell Counting Kit-8 assay and flow cytometry for the determination of cell proliferation and apoptosis, respectively, in H522 and A549 cells after OSER1-AS1 knockdown. (D and E) Cell migration and invasion assays of H522 and A549 cells transfected with small interfering (si)-OSER1-AS1 or control si-NC. *P<0.05 and **P<0.01, compared to the si-NC group. OSER1-AS1, RNA OSER1 antisense RNA 1; NSCLC, non-small cell lung cancer; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; PI, propidium iodide.