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. 2020 Jul 6;8:99. doi: 10.1186/s40478-020-00972-z

Table 1.

Study group characteristics

CAA-NH CAA-ICH P-value
N 18 11
Age (mean ± sd) 72.9 (12.4) 76.6 (4.7) 0.27 a
Sex (% female) 39 36 1.00 b
CAA grade (mean ± sd) * 3.1 (0.8) 3.5 (0.5) 0.14 b
Demented

Dementia = 12

No dementia = 3

Not reported = 2

Down Syndrome = 1

Dementia = 5

No dementia = 4

Not reported = 2

0.37 c
Location ICH N.A.

Frontal; n = 2

Fronto-parietal; n = 2

Fronto-temporal; n = 1

Temporal; n = 1

Temporo-parietal; n = 1

Parieto-occipital; n = 3

Not reported = 1

N.A.

Abbreviations: CAA-NH CAA non-haemorrhagic, CAA-ICH CAA-related ICH, N.A. not applicable. * CAA grading according to Olichney et al., [30]. aAssessed by t-test; bAssessed by Fishers exact test; cAssessed by chi-square test. See Additional files 1 and 2 for detailed pathological information reported per case