TABLE 1.
Prior definition | New definition | |
---|---|---|
Group 1 (PAH) | mPAP ⩾25 mmHg and PVR >3 WU | mPAP >20 mmHg and PVR ⩾3 WU |
PAWP ⩽15 mmHg | PAWP ⩽15 mmHg | |
No/mild lung disease or FVC ⩾70% | No/mild lung disease or FVC ⩾70% | |
Group 2 (post-capillary)# | mPAP ⩾25 mmHg | mPAP >20 mmHg |
PAWP >15 mmHg | PAWP >15 mmHg | |
PVR <3 WU | PVR <3 WU | |
Group 3 (lung disease and/or hypoxia) | mPAP ⩾25 mmHg and PVR >3 WU | mPAP >20 mmHg and PVR ⩾3 WU |
PAWP ⩽15 mmHg | PAWP ⩽15 mmHg | |
Moderate/severe lung disease¶ or FVC <70% | Moderate/severe lung disease¶ or FVC <70% | |
Group 4 (combined pre- and post-capillary) | mPAP ⩾25 mmHg | mPAP >20 mmHg |
PAWP >15 mmHg | PAWP >15 mmHg | |
PVR >3 WU | PVR ⩾3 WU |
PAH: pulmonary arterial hypertension; mPAP: mean pulmonary arterial pressure; PVR: pulmonary vascular resistance; WU: Wood Units; PAWP: pulmonary arterial wedge pressure; ILD: interstitial lung disease; FVC: forced vital capacity.
PH due to left heart disease
high-resolution computed tomography showing >20% total lung involvement due to ILD or if the total lung involvement due to ILD was 10-20% but the patient had concomitant moderate-to-severe emphysema.