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. 2020 May 27;44(2):519–532. doi: 10.3892/or.2020.7626

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Overview of the circRNA profiles (N, normal thyroid tissues; T, tumour thyroid tissues; chr, chromosome). (A) Hierarchical cluster analysis of differentially expressed circRNAs. The red and blue colours indicate high and low expression, respectively. (B) Volcano plot of differentially expressed circRNAs in PTC. The dotted line represents P=0.05. The red and green points represent circRNAs that were significantly upregulated or downregulated, respectively. (C) Chromosomal distributions of differentially expressed circRNAs. (D) RNA sequencing data of 8 circRNAs. PTC, papillary thyroid carcinoma; circRNA, circular RNA.