Table I.

Association between HPSE protein expression (immunohistochemical staining) in pancreatic cancer and clinicopathological variables.

		HPSE expression
Variables	Total	Low (n=53)	High (n=75)	χ2	P-value
Sex					0.760
Male	85	36	49	0.093
Female	43	17	26
Age (years)					0.391
≤60	54	20	34	0.735
>60	74	33	41
Size (cm)					0.373
≤4	104	45	59	0.793
>4	24	8	16
Tumor location					0.493
Head and neck	85	37	48	0.470
Body and tail	43	16	27
Vascular invasion					0.025
Negative	61	19	42	5.055
Positive	67	34	33
Differentiation					0.012
High/moderate	58	31	27	6.339
Poor and undifferentiated	70	22	48
TNM stage					0.023
I–II	62	32	30	5.163
III–IV	66	21	45

HPSE, heparanase.