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Percent probabilities of amikacin PK-PD target attainment by MIC based on total-drug plasma AUC:MIC ratio targets for Enterobacteriaceae among simulated patients with normal renal function. Abbreviations: AUC:MIC ratio, ratio of the area under the concentration-time curve from 0 to 24 hours to the minimum inhibitory concentration; MIC, minimum inhibitory concentration; PK-PD, pharmacokinetic–pharmacodynamic.
