Table 4.

Multivariate analysis on factors that influenced health-related quality of life in patients with irritable bowel syndrome

	MCS		PCS		SF-36 global health
	Regression Coefficient (95%CI)	P value	Regression Coefficient(95%CI)	P value	Regression Coefficient(95%CI)	P value
Male	reference		reference		reference
Female	2.259(−2.059,6.402)	0.281	−0.112(−3.785,3.560)	0.952	1.073(−2.446,4.593)	0.549
Age	0.036(−0.106,0.199)	0.641	−0.078(− 0.214,0.058)	0.260	− 0.021(− 0.151,0.109)	0.752
Anxiety	−1.392(−2.046,-0.684)	< 0.001	− 0.475(− 1.084,0.134)	0.126	−0.933(− 1.517,-0.350)	0.002
Depression	− 2.829(− 3.398,-2.160)	< 0.001	− 1.595(− 2.143,-1.047)	< 0.001	−2.212(− 2.737,-1.687)	< 0.001
IBS overlap
IBS only	reference		reference		reference
IBS + FD	−4.818(−10.183,0.547)	0.078	−5.594(− 10.383,-0.805)	0.022	−5.206(−9.796,-0.616)	0.026
IBS + FD + BD/FH	−8.697(−14.005,-3.390)	0.001	−9.041(−13.779,-4.302)	< 0.001	−8.869(− 13.410,-4.328)	< 0.001
IBS + BD/FH	−3.356(− 9.521,2.809)	0.285	−2.735(− 8.238,2.769)	0.329	− 3.046(− 8.320,2.229)	0.257

Abbreviations: MCS mental component summary, PCS physical component summary, SF-36 36-item Short-Form Health Survey, IBS irritable bowel syndrome, FD functional dyspepsia, BD belching disorders, FH Functional heartburn, BD/FH BD and/or FH, IBS-U unsubtyped IBS, IBS-D IBS with diarrhea, IBS-C IBS with constipation, IBS-M mixed IBS