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Competition binding curves of Famotidine (blue circles), Cimetidine (red squares), and PB-28 (green triangle), a potent sigma receptor ligand as positive control. (A) [3H](+)-pentazocine competition curves in Expi293 membranes expressing sigma-1. (B) [3H]DTG competition curves in Expi293 membranes expressing sigma-2 (TMEM97).
