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Antiepileptic drugs inhibit sodium currents of GOF mutations. (a) Representative currents recorded at −80 mV of WT and mutant Nav1.2 channels before and after application of 100 μM PHT, OXC, and CBZ. (b) Normalized inhibitory rate of sodium currents of antiepileptic drugs. Percentages of inhibition for WT and the mutations of Nav1.2 channels are evaluated by the peak current before and after application of drugs
