Table 1.
Patient characteristics
Characteristics | No (%) |
---|---|
Demographic characteristics | |
Total patients | 18 |
Grade 4 glioblastoma | 18 (100%) |
Age, y | 55 (range 48-70) |
Sex | |
Male | 10 (56%) |
Female | 8 (44%) |
Evidence for enhancing tumor on preoperative ceMRI | 18 (100%) |
MET-PET scans | |
Scan 1: Postoperative | 18 (100%) |
Scan 2: Postchemoradiation | 14 (78%) |
Tumor characteristics | |
MGMT hypermethylation status | |
Methylated | 8 (44%) |
Not methylated | 8 (44%) |
Unknown | 2 (12%) |
EGFR amplification | |
Positive | 5 (28%) |
Negative | 11 (61%) |
Unknown | 2 (12%) |
MET amplification | |
Positive | 2 (12%) |
Negative | 14 (78%) |
Unknown | 2 (12%) |
IDH-1 gene mutation status | |
Wildtype | 18 (100%) |
Mutated | 0 (0%) |
Abbreviations: ceMRI = contrast-enhanced magnetic resonance imaging; EGFR = epidermal growth factor receptor; IDH-1 = isocitrate dehydrogenase 1; MET = methionine; MGMT = O6-methylguanine-DNA methyltransferase; PET = positron emission tomography.