Table 1.
Variable | Statistic (M(SD)) |
---|---|
Age | 28.27 (6.94) |
Sex (% Female) | 37% |
Ethnicity (n(%)) | |
Chinese | 17 (41.5%) |
Japanese | 3 (7.3%) |
Korean | 19 (46.3%) |
Taiwanese | 2 (8%) |
AUDIT Total | 14.46 (5.19) |
30-Day TLFB Drinking Days | 13.66 (6.56) |
30-Day TLFB Drinks Per Drinking Day | 4.79 (2.29) |
Cigarette Smokers (n(%)) | 12 (29%) |
30-Day TLFB Cigarettes Per Day | 4.00 (4.89) |
Cannabis Users (n(%)) | 4 (10%) |
ADH1B (AA/AG/GG) | 5/7/19 |
ALDH2 (AA/AG/GG) | 0/6/35 |
OPRM1 (AA/AG/GG) | 18/17/6 |
Placebo Self-Administration % who drank (n(%)) | 39 (53%) |
Placebo Self-Administration Latency to First Drink (median) | 180 s |
Naltrexone Self-Administration % who drank (n(%)) | 31 (41%) |
Naltrexone Self-Administration Latency to First Drink (median) | 180 s |
Placebo TLFB Pre-scan Days since Last Drink | 2.39 (2.20) |
Placebo Alcohol > Water Ventral Striatum Activation | 1.44 (7.42) |
Naltrexone TLFB Pre-scan Days since Last Drink | 2.85 (1.65) |
Naltrexone Alcohol > Water Ventral Striatum Activation | 2.83 (9.08) |
Washout Period TLFB Drinks Per Drinking Day | 4.86 (3.01) |
Washout Period TLFB Cigarettes Per Day | 3.80 (4.23) |
Note. AUDIT = Alcohol Use Disorders Identification Test. TLFB = Timeline Follow-Back. Ventral Striatum contrast estimate units of measure are arbitrary units; higher values correspond to greater activation.