Supplemental Table 1.
Baseline Demographics and Disease Characteristics by Agea (n = 84)
| Characteristic | Age Group, y |
|
|---|---|---|
| <75 (n = 47) | ≥75 (n = 37) | |
| Age, y | ||
| Median | 68 | 78 |
| Range | 49-74 | 75-90 |
| Age ≥ 65 y, n (%) | 30 (64) | 37 (100) |
| Male gender, n (%) | 23 (49) | 18 (49) |
| Race, n (%) | ||
| White | 37 (79) | 24 (65) |
| Black/African American | 6 (13) | 7 (19) |
| Asian | 1 (2) | 1 (3) |
| Multiple | 0 (0) | 1 (3) |
| Missing | 3 (6) | 4 (11) |
| Ethnicity, n (%) | ||
| Hispanic/Latino | 6 (13) | 2 (5) |
| Not Hispanic/Latino | 39 (83) | 33 (89) |
| Not reported/unknown | 2 (4) | 2 (5) |
| ISS stage at initial diagnosis, n (%) | ||
| I | 14 (30) | 8 (22) |
| II | 14 (30) | 11 (30) |
| III | 12 (26) | 17 (46) |
| Unknown | 7 (15) | 1 (3) |
| Type of myeloma at initial diagnosis, n (%) | ||
| Heavy chain | ||
| IgG | 29 (62) | 21 (57) |
| IgA | 10 (21) | 6 (16) |
| IgD | 1 (2) | 0 (0) |
| IgM | 0 (0) | 1 (3) |
| Multiple | 3 (6) | 4 (11) |
| Missing | 4 (9) | 5 (14) |
| Light chain | ||
| Kappa | 33 (70) | 18 (49) |
| Lambda | 10 (21) | 17 (46) |
| Multiple | 3 (6) | 2 (5) |
| Missing | 1 (2) | 0 (0) |
| Lytic bone disease, n (%) | 20 (43) | 15 (41) |
| Extramedullary disease, n (%) | 4 (9) | 2 (5) |
| Creatinine clearance,b mL/min | ||
| Median | 81 | 63 |
| Range | 12-226 | 19-133 |
| Calculated creatinine clearance < 30 mL/min, n (%) | 3 (6) | 1 (3) |
Abbreviation: ISS = International Staging System.
a
At enrollment (or initial diagnosis for ISS stage and type of myeloma).
b
Patients aged < 75 years totaled 42 and patients aged ≥ 75 years totaled 34.