Table 4.
Effect of EADL pre-treatment on the body weight (BW), liver weight (LW) and their ratio (LW/BW) in PCM intoxicated rats.
| Group | Treatment | Dose (mg/kg) | Body weight (BW) (g) | Liver weight (LW) (g) | LW/BW (%) |
|---|---|---|---|---|---|
| Normal Control | Control | – | 208.7 ± 5.6 | 5.9 ± 0.3 | 2.8 ± 0.1 |
| Negative Control | DMSO + PCM* | – | 219.5 ± 4.7 | 9.7 ± 0.9a | 4.4 ± 0.4a |
| Positive Control | Silymarin + PCM* | 200 | 209.4 ± 4.7 | 6.9 ± 0.2b | 3.3 ± 0.2b |
| Treatment | EADL + PCM* | 50 | 215.7 ± 6.6 | 7.1 ± 0.5b | 3.3 ± 0.3b |
| 250 | 219.8 ± 7.1 | 7.8 ± 0.2b | 3.6 ± 0.4b | ||
| 500 | 217.5 ± 4.7 | 6.2 ± 0.4b | 2.9 ± 0.3b |
Values are expressed as means ± S.E.M. of six replicates.
*PCM was administered in the dose of 3 mg/kg.
aSignificant different as compared to normal control, p < 0.05.
bSignificant different as compared to negative control, p < 0.05.