Table 6.
Effect of EADL pre-treatment on the levels of SOD, CAT and MDA in liver of PCM intoxicated rats.
| Group | Treatment | Dose (mg/kg) | CAT (U/g tissue) | SOD (U/g tissue) | MDA (µM) |
|---|---|---|---|---|---|
| Normal control | DMSO + DMSO | – | 114.8 ± 1.6 | 9.7 ± 0.4 | 2.6 ± 0.6 |
| Negative control | DMSO + PCM* | – | 92.9 ± 1.9a | 4.0 ± 0.1a | 5.0 ± 0.6a |
| Positive control | Silymarin + PCM* | 200 | 109.5 ± 4.6b | 11.8 ± 1.5 | 2.6 ± 0.3b |
| Treatment | EADL + PCM* | 50 | 96.9 ± 2.7 | 5.3 ± 0.9 | 2.6 ± 0.7b |
| 250 | 112.7 ± 5.7b | 7.9 ± 0.2b | 3.0 ± 0.3b | ||
| 500 | 115.2 ± 3.4b | 8.3 ± 0.5b | 2.7 ± 0.7b |
Values are expressed as means ± S.E.M. of six replicates.
*PCM was administered in the dose of 3 mg/kg.
aSignificant different as compared to normal control, p < 0.05.
bSignificant different as compared to negative control (DMSO + PCM), p < 0.05.