Table 4.

Pooled hazard ratios and 95% confidence intervals.

	Number of studies	Pooled HR (95% CI), fixed effects	Pooled HR (95% CI), random effects	Ri*	Q test p Value
Overall survival
Overall	11	1.45 (1.17–1.80)	1.46 (1.12–1.89)	0.26	.21
High quality	6	1.48 (1.18–1.86)	1.51 (1.11–2.06)	0.38	.13
Low quality	5	1.21 (0.64–2.29)	1.21 (0.64–2.29)	0.00	.57
Full adjustment	4	1.48 (1.18–1.86)	1.51 (1.11–2.06)	0.38	.13
Asian	5	2.01 (1.42–2.86)	2.01 ( 1.42–2.86)	0.00	.45
Non-Asian	6	1.19 (0.91–1.57)	1.19 (0.91–1.57)	0.00	.45
Tongue	4	1.18 (0.84–1.66)	1.22 (0.66–2.27)	0.66	.04
Mixed subsites	7	1.48 (1.14–1.91)	1.48 (1.10–2.00)	0.22	.29
Use of M75 antibody	3	1.93 (1.29–2.88)	1.93 (1.29–2.88)	0.00	.39
Use of other antibodies	8	1.29 (1.00–1.67)	1.29 (0.96–1.75)	0.21	.27
Use of 10% cut-off point	6	1.72 (1.14–2.59)	1.69 (1.06–2.69)	0.17	.31
Use of other cut-off points	5	1.36 (1.06–1.75)	1.36 (0.98–1.88)	0.39	.17
Disease-free survival
Overall	5	1.98 (1.18–3.32)	2.12 (1.02–4.43)	0.40	.19
Asian	4	1.81 (1.06–3.09)	1.82 (0.90–3.69)	0.34	.25
Tongue	2	1.51 (0.79–2.88)	1.27 (0.43–3.74)	0.57	.21
Mixed subsites	3	3.24 (1.35–7.76)	3.58 (1.26–10.12)	0.26	.39
Use of 10% cut-off point	3	1.82 (0.99–3.33)	1.85 (0.59–5.77)	0.65	.12
Use of other cut-off points	2	2.50 (0.91–6.89)	2.98 (0.69–12.91)	0.48	.20
Locoregional control
Overall	2	1.01 (0.50–2.02)	1.01 (0.50–2.02)	0.00	.80
Disease specific survival
Overall	6	1.00 (0.99–1.01)	1.35 (0.78–2.33)	1.00	.03
Asian	2	0.55 (0.21–1.44)	0.55 (0.21–1.44)	0.00	.41
Non-Asian	4	1.00 (0.99–1.01)	1.79 ( 0.90–3.54)	1.00	.01
Tongue	2	0.55 (0.21–1.44)	0.55 (0.21–1.44)	0.00	.41
Mixed subsites	4	1.00 (0.99–1.01)	1.79 (0.90–3.54)	1.00	.02

*R_i stands for the proportion of the total variance due to between studies variance.