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Presence of crystal contacts, indicated with yellow dashes, for residue Arg14 in 2VB1 (panel a) and absence of contacts for the same residue in 6F1O. Arg14 is indicated by an arrow. Crystal symmetry mate molecules are shown in cyan, brown and magenta for both structures. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
