Table 1. Spearman’s rank correlation between genomic features and two measures of sequence evolution.

Feature	SIFT-score		Nucleotide diversity
	Pairwise	Partiala	Pairwise	Partiala
GC%	0.17*	0.10*	−0.05*	−0.03*
Exonic bp	0.01	∼0	∼0	−0.03*
Intronic bp	−0.01	∼0	−0.08*	−0.01
Splice variants	−0.05*	−0.04*	−0.01	∼0
Centromere distance	−0.06*	−0.05*	−0.27*	−0.11*
Codon usage	−0.08*	−0.03*	∼0	0.03*
Recombination rate	0.05*	0.02*	0.29*	0.13*
Mutation rate	0.01	∼0	0.10*	0.04*
TE distance	−0.02*	∼0	−0.14*	−0.02
ACR distanceb	−0.09*	0.01	−0.10*	∼0
ACR%b	0.11*	0.01	0.11*	0.04*
Methylation level	−0.02	∼0	−0.05*	0.06*
Methylation variability	0.01	0.01	0.12*	0.08*
Connectivity	0.12*	0.02	−0.17*	−0.12*
Expression level	0.25*	0.16*	−0.06*	−0.06*
Expression variability	−0.10	−0.04*	0.18*	0.09*

^aPartial correlation after controlling for all other features (Kim 2015).

^bAccessible chromatin region.

^*P < 0.05 (Bonferroni corrected).