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. 2020 Jun 11;105(8):2789–2802. doi: 10.1210/clinem/dgaa354

Table 5.

Mixed-effects regression models of metabolic outcomes in male and female participants

Male participants
  Outcome Fixed factor β coefficient 95% CI P
4-h postdinner AUC-glucose (mg/dL*h) Late dinner 84.1 42.3 to 125.9 <.001
Postdinner FAO rate (%/h) Late dinner –.6 –1.18 to 0.01 0.05
Female participants
  Outcome Fixed factor β coefficient 95% CI P
4-h postdinner AUC-glucose (mg/dL*h) Late dinner 73.9 45.7 to 102.0 <.001
Post-dinner FAO rate (%/h) Late dinner –.8 –1.74 to 0.07 0.07

This is a subgroup analysis performed in male and female participants, respectively. β coefficients are obtained from the fixed part of mixed-effects models, in which each metabolic outcome was regressed against the fixed factor and the random factor subject number. Bold P values mean statistically significant.

Abbreviations: AUC, area under the curve; FAO, fatty acid oxidation; Late dinner, 0 = routine dinner visit, 1 = late dinner visit; postdinner FAO rate, cumulative FAO at 14 hours after dinner divided by 14 hours.