Table 5.
Mixed-effects regression models of metabolic outcomes in male and female participants
| Male participants | ||||
|---|---|---|---|---|
| Outcome | Fixed factor | β coefficient | 95% CI | P |
| 4-h postdinner AUC-glucose (mg/dL*h) | Late dinner | 84.1 | 42.3 to 125.9 | < .001 |
| Postdinner FAO rate (%/h) | Late dinner | –.6 | –1.18 to 0.01 | 0.05 |
| Female participants | ||||
| Outcome | Fixed factor | β coefficient | 95% CI | P |
| 4-h postdinner AUC-glucose (mg/dL*h) | Late dinner | 73.9 | 45.7 to 102.0 | < .001 |
| Post-dinner FAO rate (%/h) | Late dinner | –.8 | –1.74 to 0.07 | 0.07 |
This is a subgroup analysis performed in male and female participants, respectively. β coefficients are obtained from the fixed part of mixed-effects models, in which each metabolic outcome was regressed against the fixed factor and the random factor subject number. Bold P values mean statistically significant.
Abbreviations: AUC, area under the curve; FAO, fatty acid oxidation; Late dinner, 0 = routine dinner visit, 1 = late dinner visit; postdinner FAO rate, cumulative FAO at 14 hours after dinner divided by 14 hours.