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. 2020 Jun 5;34(Suppl 1):1–51. doi: 10.1038/s41433-020-0961-6

Table 1.

How non-proliferative retinopathy classification systems have evolved (adapted with permission from ref. [179] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587728/).

Classification System Classification
Airlie House 1968 (level) [300] (0)None (1) Mild to Moderate (2) Moderate to severe
ETDRS, 1991 (level) [277] (10) Diabetic retinopathy absent (20) Microaneurysms only (35) Mild non proliferative retinopathy (43) Moderate non proliferative retinopathy (47) Moderately severe non proliferative retinopathy (53 A-D) Severe non proliferative retinopathy
ICDRSS, 2003 (level) [278] No apparent retinopathy Mild non proliferative retinopathy Moderate non proliferative retinopathy Severe non proliferative retinopathy
National Screening Committee UK, 2003 (level) [275] (R0) None (R1) Background diabetic retinopathy (R2) Pre proliferative diabetic retinopathy
SDRGS, 2003 (level) [301] (R0) None (R1) Mild background diabetic retinopathy (R2) Moderate background diabetic retinopathy (R3) Severe background diabetic retinopathy
DR Deep Learning Algorithm, 2016 [297] NA Moderate non proliferative retinopathy Severe non proliferative retinopathy

ICDRSS International Clinical Diabetic Retinopathy Disease Severity Scale, SDRGS Scottish Diabetic Retinopathy Grading Scheme.