. 2014 Dec 4;4:133–151. doi: 10.2147/DNND.S70079

Table 5.

Summary of pathology-related changes in paired-pulse transcranial magnetic stimulation-based measures of neurophysiology

	Paired-pulse TMS
	SICI	ICF	LICI	IHI	SAI	LAI	CMCT
PD	↓ rest⁴⁹^,⁵³^–⁵⁵	↓⁵⁶^–⁵⁸	↑⁵³^,⁵⁵^,⁵⁹	H₀¹⁸⁸	H₀²⁸	↓²⁸	H₀⁴⁹
	H₀ active⁵⁹^,¹⁸⁶		↓¹⁸⁷	↓¹⁸⁸	↓²⁸
HD	↓⁸⁹^,²¹¹	↑¹⁸⁹			↓¹²³		H₀⁸⁹^,¹¹⁹	↑¹⁹⁰
	H₀¹⁸⁹	↓⁸⁹
ALS	↓¹²⁸^,¹³⁶^,¹³⁸^,¹³⁹^,¹⁵²^,¹⁵⁶^,¹⁹¹^–¹⁹³^,²²⁴	↑¹⁵²					↑¹³⁰^,¹⁵²
							H₀ ¹²⁹^–¹³¹^,¹⁵⁰^,¹⁵³^,¹⁵⁴^,¹⁶⁵^,²¹⁶
MS	↓¹⁸¹			↑ latency¹⁸⁰^,¹⁵⁴			↑¹⁷²^,¹⁷⁴^,¹⁸¹^,¹⁸⁵^,¹⁹⁵
				↓ durat1on¹⁵⁴
				↑ durat1on¹⁸⁰

Abbreviations: TMS, transcranial magnetic stimulation; SICI, short-interval intracortical inhibition; ICF, intracortical facilitation; LICI, long-interval intracortical inhibition; IHI, interhemispheric inhibition; SAI, short-afferent inhibition; LAI, long-afferent inhibition; CMCT, central motor conduction time; H₀, null result; ALS, amyotrophic lateral sclerosis; PD, Parkinson's disease; MS, multiple sclerosis; HD, Huntington's disease; ↑, increase; ↓, decrease.