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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Mol Genet Metab. 2020 May 11;130(3):183–196. doi: 10.1016/j.ymgme.2020.05.003

Figure 4.

Figure 4.

Donors show unique responses of propionyl-CoA (P-CoA) production from each amino acid source. Each P-CoA amino acid or α-ketoacid precursor was titrated from 10 μM to 3000 μM in multiple propionic acidemia (PA) donors, while keeping the rest of the amino acids at low concentrations and P-CoA levels were measured (N=3-6 biological replicates/dose; N=1 technical replicate/biological replicate).