Table 1. Demographic data and clinical characteristics of patients.
| Parameter | Healthy | POAG | P Valueǂ | |
|---|---|---|---|---|
| Mild | Moderate/Severe | |||
| Number of eyes (patients) | 23(15) | 30(20) | 22(16) | |
| Age (years) | 69±5.2 | 70.2±8.3 | 71.9±8.2 | 0.573 |
| Gender (Male/Female) | 6/9 | 8/12 | 9/6 | 0.429 |
| Self-Reported History of Hypertension (patients) | 8(53.3) † | 9(45† | 9(60) † | 0.674 |
| Self-Reported History of Diabetes (patients) | 4(26.7) † | 4(20) † | 2(13.3) † | 0.622 |
| Number of GlaucomaMedications | 0 | 1.5±0.9 | 2.1±1.1 | 0.049 |
| Eyes on Timolol | 0 | 13(43.3) † | 13(59.1) † | 0.401 |
| Eyes on Brymonidine | 0 | 3(10) † | 8 (36.4) † | 0.037 |
| Eyes on ProstaglandinAnalogs | 0 | 20(66.7) † | 8(36.4) † | 0.048 |
| Eyes on Carbonic Anhydrase Inhibitors | 0 | 10(33.3) † | 16(72.7) † | 0.011 |
| History of Glacuoma Surgery (eyes) | 0 | 2(6.7) † | 3 (13.6) † | 0.639 |
| BCVA (Snellen) | 1(1–1)* | 1(1–1)* | 1(1–1)* | 0.270 |
| CCT (microns) | 540(532–549)* | 537.5(497.5–564.5)* | 517(486–540)* | 0.485 |
| IOP (mmHg) | 17.8±2.1 | 18.3±2.1 | 17.6±2.5 | 0.552 |
| AxialLength (mm) | 22.9±0.7 | 23.2±1.0 | 23.37±0.8 | 0.296 |
Mean (standard deviation).
*Median (interquartilerange).
†n (%).
ǂStatistical significance tested by ANOVA or Kruskal-Wallis test (for continuous variables) and by chi-square or Fisher exact test (for categorical variables).
Abbreviations: POAG = primary open-angle glaucoma; BCVA = best corrected visual acuity; CCT = central corneal thickness; IOP = intraocular pressure.