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. 2020 Jul 6;15(7):e0235571. doi: 10.1371/journal.pone.0235571

Table 5. Area under the receiver operating characteristic curve and diagnostic sensitivity of the structural to diagnose primary open-angle glaucoma.

Parameter AUROC (95% CI) Sensitivity (95%specificity) P Value for pairwise AUROC comparison*
SVP whole VD DVP/ SVP index pRPC VD GCC average
SVP whole VD 0.92 (0.85–0.98) 0.74 - - - -
DVP/SVP VDindex 0.89 (0.81–0.96) 0.65 0.526 - - -
pRPC VD 0.92 (0.86–0.98) 0.79 0.827 0.353 - -
GCC average 0.91 (0.83–0.98) 0.5 0.8 0.658 0.645 -
pRNFLglobal 0.94 (0.9–0.99) 0.77 0.4 0.079 0.299 0.147

Sensitivities at 95% specificity were evaluated.

* DeLong’s or bootstrap test.

Abbreviations: AUROC = area under the receiver operating characteristic curve; CI = confidence interval; VFI = visual field index; MD = mean deviation; PSD = pattern standard deviation; SVP = superficial vascular plexus; DVP = deep vascular plexus; pRPC = peripapillary radial peripapillary capillaries; VD = vessel density; GCC = ganglion cell complex; pRNFL = peripapillary retinal nerve fiber layer.