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. 2020 Jun 23;16(6):e1008308. doi: 10.1371/journal.ppat.1008308

Fig 4. The effect of miRNAs on HCV propagation and the introduction of G28A mutation.

Fig 4

(A) Infectious titer in the culture medium on serial passage of 751-122KO cells in the presence of mimic control, miR-122, miR-25-5p, miR-504-3p, miR-574-5p and miR-1236-5p. (B) Mutation of G28A in the 5’UTR of HCV was identified in all independently isolated HCV propagated in Fig 4A. Arrows indicate the position of nt28 in the 5’UTR of HCV. Each RNA base is represented as a colored peak: A, green; U, red; G, black; and C, blue.