Figure 1.

The schematic figure implies the interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the cell structures, clockwise including cell membrane, endoplasmic reticulum, Golgi, extracellular matrix, followed by hallmarks of aging such as senescence cells, inflammation, genome instability, mitochondrial function, telomere length, epigenetics, and stem cell exhaustion. The entire cell fitness is required to combat viral infection, and coronavirus engages cell systems.