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. 2020 May 22;48(12):6685–6698. doi: 10.1093/nar/gkaa370

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Classification of TE targeting strategies in context of host transcription. A proposed model depicting occupation of TEs at genomic locations with different expression characteristics. Type-A and type B transposons primarily target open chromatin regions where active transcription occurs. Integration of the type-A transposons associates with RNA Pol II transcription initiation. Factors that directly mediate transposase-recruitment to TSSs are yet to be identified. Targeting of the type-B transposons associates with both RNA Pol II transcription initiation and termination.