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Mapping PTs across the S. enterica genome by Nick-seq. (A) Schematic showing the iodine cleavage method for converting PTs to strand-breaks. (B) the number of PT modification sites identified by Nick-seq in different sequence motifs. A total of 11 684 breaks were detected at the expected GAAC/GTTC motif, with single- and double-strand PTs denoted by a red ‘S’. The blow up shows minor modification motifs.
