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. 2020 Jun 2;48(12):6445–6457. doi: 10.1093/nar/gkaa469

Figure 5.

Figure 5.

Lack of correlation between Thr codon usage and tRNAThr abundance and potential fragmentation of tRNAThr(G4:U69). (A) Comparison of the estimated relative frequency of the Thr codon usage and the relative counts of different tRNAThr isoacceptor families in the human genome indicates a lack of correlation between codon usage and tRNA abundance. (B) G4:U69 base pair may play a role in stabilizing tRNAThr fragments. The fragments (5′- and 3′-halves) are listed according to their predicted minimum free energy from low to high, putting the most stable tRNA fragments on the top, which are from G4:U69-containing tRNAThr. The secondary structure of potential tRNAThr fragments and their minimum free energy are predicted by RNAfold server. The secondary structure of representative fragments is shown aside. The sizes of tRNA 5′- and 3′-halves are approximated based on the size ranges of tRNA fragments reported so far.