The effect of retigabine on the chemosensitivity of SKBR3 breast cancer cells to paclitaxel. (A) MTT assay of SKBR3 cells treated with 10 μM retigabine plus different concentrations of paclitaxel (0 – 100 nM) at 24 hrs, 48 hrs, and 72 hrs. (B) MTT assay of SKBR3 cells treated with 10 nM paclitaxel plus different concentration of retigabine at 72 hrs. P = 0.09, F(3,6) = 3.487, one-way ANOVA. Dots in each column represent one independent experiment. Each experiment was performed three times.