Table 1.
Correlation of miR-4429 with Clinicopathological Features of CC Patients
| Clinicopathological Parameters | n | miR-4429 | χ2 | P-value | |
|---|---|---|---|---|---|
| Low Expression | High Expression | ||||
| Age (Y) | 0.362 | 0.548 | |||
| <50 | 43 | 20 (39.22) | 23 (45.10) | ||
| ≥50 | 59 | 31 (60.78) | 28 (54.90) | ||
| Histological type | 2.590 | 0.108 | |||
| Adenocarcinoma | 42 | 25 (49.02) | 17 (33.33) | ||
| Squamous cell carcinoma | 60 | 26 (50.98) | 34 (66.67) | ||
| FIGO staging | 7.016 | 0.008 | |||
| Ib-IIa | 39 | 13 (25.49) | 26 (50.98) | ||
| IIb-IIIa | 63 | 38 (74.51) | 25 (49.02) | ||
| Lymph node metastasis | 6.668 | 0.001 | |||
| No | 47 | 17 (33.33) | 30 (58.82) | ||
| Yes | 55 | 34 (66.67) | 21 (41.18) | ||
| Pathological grading | 2.914 | 0.088 | |||
| High/Moderate differentiation | 70 | 31 (60.78) | 39 (76.47) | ||
| Low differentiation | 32 | 20 (39.22) | 12 (23.53) | ||
| Invasive depth | 1.998 | 0.158 | |||
| <1/2 | 41 | 17 (33.33) | 24 (47.06) | ||
| ≥1/2 | 61 | 34 (66.67) | 27 (52.94) | ||
| Tumor diameter (cm) | 0.640 | 0.424 | |||
| <4cm | 44 | 20 (39.22) | 24 (47.06) | ||
| ≥4cm | 58 | 31 (60.78) | 27 (52.94) | ||
| HPV infection | 3.304 | 0.069 | |||
| Negative | 26 | 9 (17.65) | 17 (33.33) | ||
| Positive | 76 | 42 (82.35) | 34 (66.67) | ||
Abbreviations: miR, microRNA; CC, cervical cancer; FIGO, Federation of Gynecology and Obstetrics; HPV, human papillomavirus.