Alloxazine alters macrophage function in livers of MCD mice.Liver sections stained for F4/80 and cleaved caspase-3, 40× magnification (A). Sum fluorescent intensity of F4/80 (B), cleaved caspase-3 (C), merged fluorescence of F4/80 and cleaved caspase-3 (MERGE) (D) staining and average macrophage area (E). White bars represent CTR+Veh, light gray bars represent CTR+ALX, dark gray bars represent MCD+Veh, and dark bars represent MCD+ALX. Different lowercase letters denote a significant difference (P<.05, n=3–8). All data are presented as mean ± standard deviation.