FIG 3.

Effect of immune modulators on the position of an individual on the DRF parabola. For those with weak immune responses (left side of the x axis), treatment with an immune modulator that enhances immunity may move them to a position to the right representing reduced damage. Conversely, for those with disease resulting from immune-mediated host damage (right side of the x axis), treatment with an immune modulator that diminishes the intensity of the immune response may move them to a position to the left representing reduced damage.