Table 2. Pathologic findings in patients with acute tubular necrosis or interstitial nephritis.
| Variables | ATN (n = 116) | AIN (n = 137) | P value |
|---|---|---|---|
| No. of glomerulus | 19.9 ± 15.0 | 24.6 ± 18.8 | 0.035 |
| Global glomerulosclerosis | 7.9 ± 10.4 | 10.1 ± 11.9 | 0.155 |
| Tubular atrophy | 76 (70.4) | 98 (74.2) | 0.504 |
| Tubular necrosis | 95 (88.0) | 86 (65.2) | < 0.001 |
| Interstitial inflammation | 86 (79.6) | 131 (99.2) | < 0.001 |
| Tubulitis | 7 (6.5) | 68 (51.5) | < 0.001 |
| Interstitial fibrosis | 42 (38.9) | 85 (64.9) | < 0.001 |
| Interstitial edema | 62 (57.4) | 49 (37.1) | 0.002 |
| Vascular lesion | 34 (31.8) | 61 (49.2) | 0.007 |
Data are presented as mean ± standard deviation or number (%).
ATN = acute tubular necrosis, AIN = acute interstitial nephritis.