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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Mol Cell Cardiol. 2020 May 1;143:120–131. doi: 10.1016/j.yjmcc.2020.04.032

Figure 10. Schematic diagram illustrates the potential for EV-enriched miRNA27a* to contribute to cardiac hypotrophy through intercellular communication with cardiac fibroblasts.

Figure 10.

Under cardiac stress, cardiac fibroblasts secrete EV-enriched miRNA-27a* and/or miRNA-21*, which are transported to cardiomyocytes and regulates the expression of PDLIM5, leading to cardiac hypertrophy.