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. 2020 Jul 1;9(6):bio050575. doi: 10.1242/bio.050575

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© 2020. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — Inactivation of the Wnt/JNK signaling pathway reversed the inhibition of cell proliferation by the combination of Wnt7a overexpression and irradiation. (A) The expression of p-JNK (Thr183/Try185) and JNK (Total) were determined by western blot analysis in H1650 and A549 cells treated with SP600125. (B) Proliferation rate calculated for H1650 and A549 treated with SP600125 and/or Wnt7a overexpression. The cell proliferation rate was determined by the MTT assay after irradiation (4 Gy). Results are representative of triplicate experiments.