Table 2.
Multivariable Cox proportional hazards regression analysis of overall and relapse-free survivals in the training group
| Variable | Overall survival | Relapse-free survival | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age (year) | 0.69 (0.24-1.99) | 0.580 | 2.47 (0.75-8.16) | 0.207 |
| WHO high-risk histology | 0.56 (0.14-2.28) | 0.545 | 0.70 (0.13-3.86) | 0.639 |
| Surgery versus non-surgery | 2.00 (0.56-7.19) | 0.444 | 0.29 (0.08-1.00) | 0.107 |
| AJCC stage III − IV versus I − II | 2.43 (0.54-11.00) | 0.366 | 3.10 (0.59-16.36) | 0.239 |
| ECOG 2 or N2c − N3 | 5.90 (1.54-22.60) | 0.026 | 14.93 (2.38-93.72) | 0.014 |
| Subgroup 3 PET pattern | 6.30 (2.14-18.56) | 0.004 | 3.94 (1.44-10.76) | 0.024 |
Abbreviations: HR hazard ratio; CI confidence interval; WHO World Health Organization; AJCC American Joint Committee on Cancer; ECOG Eastern Cooperative Oncology Group; PET
positron emission tomography