Fig. 6.

APC-treated CL4176 worms are effective in preventing protein aggregation and Aβ reduction. a Effect of APC on the reduction of Aβ(1–42)-associated paralysis phenotype in CL4176 animals. APC-treated worms showed delay in paralysis as compared to the control. b Representative image of APC-treated and -untreated CL4176 worms were visualized by using Thioflavin-T staining. APC-treated worms (CL4176) showed reduced intensity compared to the control (untreated CL4176) and higher than that of wild type (N2 Bristol). c Image J software quantification showed the fluorescence intensity in the following order: CL4176 > APC > wild type